Netupitant Impurity 18 CAS CATO-C4X-122318
| CAS No. | CATO-C4X-122318 |
| Molecular Formula | C17H19ClN2O |
| Molecular Weight | 302.80 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Netupitant Impurity 18 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 302.80 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Netupitant Impurity 18 (CAS CATO-C4X-122318) is a certified pharmaceutical impurity reference standard with the molecular formula C17H19ClN2O and a molecular weight of 302.80 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Netupitant Impurity 18 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H19ClN2O |
| Molecular Weight | 302.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Netupitant Standards
- Netupitant Impurity 16 (CAS 2973069-91-7)
- Netupitant Impurity 17 (CAS CATO-C4X-122317)
- Netupitant Impurity 19 (CAS CATO-C4X-122319)
- Netupitant Impurity 20 (CAS CATO-C4X-122320)
- Netupitant Impurity 21 (CAS CATO-C4X-122321)
- Netupitant Impurity 24 (CAS 1314722-26-3)
- Netupitant Impurity 25 (CAS 1314651-44-9)
- Netupitant Impurity 44 (CAS CATO-C4X-122344)
Recommended Standards
- N-(tert-Butyl)-6-chloro-4-(o-tolyl)nicotinamide (CAS 342417-04-3)
- N-(3-chloro-1-tetrahydropyran-2-yl-pyrazolo[4,3-c]pyridin-6-yl)acetamide (CAS 2708286-43-3)
- Bexagliflozin Impurity 6 (CAS CATO-C4X-33226)
- N-(3-Amino-4-chlorophenyl)-4-(tert-butyl)benzamide (CAS 926217-29-0)
- Simvastatin EP Impurity A(Sodium Salt) (CAS 101314-97-0)
- Empagliflozin Impurity 238 (CAS CATO-C4X-1065238)
- Trazodone Impurity 25 (CAS CATO-C4X-177225)
- (3S,4R)-4-(Naphthalen-2-yl)pyrrolidine-3-carboxylic acid (CAS 1049978-40-6)
- (1-Methyl-5-nitro-1H-pyrazol-3-yl)methanol (CAS 1260659-40-2)
- 4-(2-Hydroxyethyl)-5-methyl-2-phenyl-1-((2,4,6-trichlorophenyl)sulfonyl)-1,2-dihydro-3H-pyrazol-3-one (CAS 866039-78-3)
- 4-Cyclopropoxy-2-iodo-N,N-dimethylbenzamide (CAS 1243465-52-2)
- 2-(2-Bromoethyl)anisole (CAS 36449-75-9)
- 4-Amino-3-(5-bromothiophen-2-yl)butanoic acid hydrochloride (CAS 2138278-38-1)
- Semaglutide Impurity 186 (CAS CATO-C4X-2226186)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com