Diltiazem Impurity 20 CAS 132830-16-1
| CAS No. | 132830-16-1 |
| Molecular Formula | C16H15NO3S |
| Molecular Weight | 301.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Diltiazem Impurity 20 (CAS 132830-16-1), a pharmacopoeial impurity reference standard (molecular formula C16H15NO3S, MW 301.36 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Diltiazem Impurity 20 (C16H15NO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Diltiazem Impurity 20 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H15NO3S |
| Molecular Weight | 301.36 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Diltiazem Standards
- Diltiazem 2-Epimer O-Desacetyl N-Desdimethylaminoethyl Impurity (CAS 132830-17-2)
- Diltiazem Impurity 21 (CAS 42399-51-9)
- Diltiazem EP Impurity E (CAS 42399-49-5)
- Diltiazem Impurity N1 (CAS 42399-48-4)
- Diltiazem Impurity N2 (CAS 42399-50-8)
- Diltiazem Impurity 18 (CAS 131613-02-0)
- Diltiazem Impurity 23 (CAS 119009-50-6)
- Diltiazem Impurity 33 (CAS CATO-C4X-136833)
Recommended Standards
- Omeprazole Impurity 38 (CAS CATO-C4X-125538)
- Tirofiban Impurity 9 (CAS 2250244-28-9)
- Tirofiban Impurity 23 (CAS 149490-60-8)
- Nebivolol Impurity 16 (CAS 99199-91-4)
- Sofosbuvir Impurity 79 (CAS 863329-66-2)
- Imatinib Impurity 94 (CAS CATO-C4X-106894)
- Lurbinectedin Impurity 15 (CAS 2248127-59-3)
- Bromfenac sodium (CAS 91714-93-1)
- N-((2-(Dimethylamino)-6-methylpyrimidin-4-yl)methyl)pentanamide (CAS 1797224-47-5)
- Methyl 3-fluoro-4-((2-hydroxybenzylidene)amino)benzoate (CAS 1296225-22-3)
- 3-Amino-4-chlorophenol hydrochloride (CAS 1881330-36-4)
- Dapagliflozin Impurity N9 (CAS 2452300-81-9)
- 3-[4-(tert-Butyl)-2-chlorophenoxy]pyrrolidinehydrochloride (CAS 1220035-98-2)
- Semaglutide impurity 196 (CAS CATO-C4X-2226196)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com