Halometasone Impurity N1 CAS 136132-00-8
| CAS No. | 136132-00-8 |
| Molecular Formula | C20H23ClF2O3 |
| Molecular Weight | 384.84 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Halometasone Impurity N1 (CAS 136132-00-8), a pharmacopoeial impurity reference standard (molecular formula C20H23ClF2O3, MW 384.84 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C20H23ClF2O3, Halometasone Impurity N1 contains a steroid core, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 384.84 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Halometasone Impurity N1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H23ClF2O3 |
| Molecular Weight | 384.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
Related Halometasone Standards
- Halometasone Impurity 3 (CAS 67212-85-5)
- Halometasone impurity 14 (CAS CATO-C4X-144614)
- Halometasone Impurity 9 (CAS CATO-C4X-14469)
- Halometasone Impurity N2 (CAS 80157-55-7)
- Halometasone impurity 15 (CAS CATO-C4X-144615)
- Halometasone impurity 17 (CAS 35540-75-1)
- Halometasone Impurity 4 (CAS CATO-C4X-14464)
- Halometasone Impurity 67 (CAS CATO-C4X-14467)
Recommended Standards
- Tetrakis(trimethylsilyl) Orthosilicate (CAS 3555-47-3)
- 2,3,5-Tribromocinnamic acid (CAS 1262012-67-8)
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- 2,4,6-Tribromophenyl acrylate (CAS 3741-77-3)
- Brexpiprazole Impurity 53 (CAS 102-92-1)
- Rosuvastatin Impurity 138 (CAS CATO-C4X-1169138)
- Pyronaridine Impurity 18 (CAS CATO-C4X-297818)
- ((2-Methoxyphenyl)ethynyl)trimethylsilane (CAS 40230-91-9)
- (S)-Benzyl 2-((tert-butoxycarbonyl)amino)-3-(quinolin-6-yl)propanoate (CAS 1263376-66-4)
- 5-Chloro-1H-pyrrolo[2,3-b]pyridine-4-carbaldehyde (CAS 1015610-39-5)
- 2-(Aminomethyl)-4-cyano-6-(difluoromethyl)-3-nitropyridine (CAS 1807155-72-1)
- 6-Fluoropyrazolo[1,5-a]pyrimidin-5-amine (CAS 1610021-97-0)
- Tert-butyl 3-(2-aminoanilino)azetidine-1-carboxylate (CAS 1513681-34-9)
- Semaglutide impurity 33 (CAS CATO-C4X-222633)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com