Halometasone Impurity N4 CAS 136154-83-1
| CAS No. | 136154-83-1 |
| Molecular Formula | C44H54Cl2F4O10 |
| Molecular Weight | 889.79 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 889.79 g/mol gives Halometasone Impurity N4 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Halometasone Impurity N4 (CAS 136154-83-1) is a certified pharmaceutical impurity reference standard with the molecular formula C44H54Cl2F4O10 and a molecular weight of 889.79 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system, Halometasone Impurity N4 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 889.79 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Halometasone Impurity N4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C44H54Cl2F4O10 |
| Molecular Weight | 889.79 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
Related Halometasone Standards
- Halometasone Impurity 1 (CAS 23961-24-2)
- Halometasone impurity 11 (CAS CATO-C4X-144611)
- Halometasone impurity 16 (CAS CATO-C4X-144616)
- Halometasone Impurity N3 (CAS 23961-22-0)
- Halometasone Impurity 2 (CAS CATO-C4X-14462)
- Halometasone Impurity 8 (CAS 28895-70-7)
- Halometasone impurity 12 (CAS CATO-C4X-144612)
- Halometasone impurity 10 (CAS CATO-C4X-144610)
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