Lubiprostone Impurity 10 CAS 136790-72-2
| CAS No. | 136790-72-2 |
| Molecular Formula | C20H28F2O5 |
| Molecular Weight | 386.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Lubiprostone Impurity 10 (CAS 136790-72-2), a pharmacopoeial impurity reference standard (molecular formula C20H28F2O5, MW 386.43 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Lubiprostone Impurity 10 (C20H28F2O5) is characterized by a steroid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H28F2O5 |
| Molecular Weight | 386.43 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F-containing |
Related Lubiprostone Standards
- Lubiprostone Impurity 17 (CAS 136790-73-3)
- Lubiprostone Impurity 27 (CAS CATO-C4X-113627)
- Lubiprostone (CAS 136790-76-6/333963-40-9)
- Lubiprostone Impurity 18 (CAS 201226-21-3)
- Lubiprostone Impurity 3 (CAS 1263283-38-0)
- Lubiprostone Impurity 30 (CAS 2743427-14-5)
- Lubiprostone Impurity 31 (CAS CATO-C4X-113631)
- Lubiprostone Impurity 32 (CAS CATO-C4X-113632)
Recommended Standards
- Ethyl 4-((3-cyano-6-methyl-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinolin-2-yl)thio)butanoate (CAS 626228-63-5)
- Ethyl (E)-3-(2-(benzyloxy)-4-((2-methoxyethoxy)methoxy)phenyl)acrylate (CAS 1016896-51-7)
- Ethyl (2-((3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)acetyl)glycinate (CAS 896678-12-9)
- 2,6-Bis(benzenesulfonyl)benzaldehyde (CAS 1020722-19-3)
- Lenvatinib Impurity 91 (CAS CATO-C4X-114091)
- Ambrisentan Impurity 5 (CAS 178306-51-9)
- Tadalafil Impurity 133 (CAS 171596-44-4)
- 2-(2-Chlorophenyl)-1-{[3-(trifluoromethyl)phenyl]methoxy}-1H-1,3-benzodiazole (CAS 338791-20-1)
- 4-Chloro-N-(9H-fluoren-9-ylidene)aniline (CAS 5455-00-5)
- (1-Cyclopentylpiperidin-4-yl)methanamine dihydrochloride (CAS 1185300-51-9)
- 4,4'-(5,6-Dimethylbenzo[c][1,2,5]thiadiazole-4,7-diyl)dibenzoic acid (CAS 2758181-33-6)
- Dihydro-α-terpineol (CAS 498-81-7)
- n-[2-(aminomethyl)cyclopentyl]methanesulfonamide hydrochloride, mixture of diastereomers (CAS 1384431-21-3)
- Peptide-GMF (CAS CATO-CPTD788469)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com