Valsartan Impurity 73 CAS CATO-C4X-105773
| CAS No. | CATO-C4X-105773 |
| Molecular Formula | C25H31N5O3 |
| Molecular Weight | 449.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 449.55 g/mol gives Valsartan Impurity 73 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Valsartan Impurity 73 (CAS CATO-C4X-105773, C25H31N5O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Valsartan Impurity 73 (C25H31N5O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Valsartan Impurity 73 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H31N5O3 |
| Molecular Weight | 449.55 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Valsartan Standards
- Valsartan Impurity 106 (CAS CATO-C4X-1057106)
- Valsartan Impurity 112 (CAS CATO-C4X-1057112)
- Valsartan Impurity 120 (CAS 137863-48-0)
- Valsartan Impurity 125 (CAS 1894176-40-9)
- Valsartan USP Related Compound E (CAS 137863-17-3)
- Valsartan Impurity 74 (CAS CATO-C4X-105774)
- Valsartan Impurity 75 (CAS CATO-C4X-105775)
- Valsartan Impurity 76 (CAS CATO-C4X-105776)
Recommended Standards
- Valsartan Impurity 77 (CAS CATO-C4X-105777)
- Valsartan Impurity 78 (CAS CATO-C4X-105778)
- CAS CATO-C3D-4200 (CAS CATO-C3D-4200)
- Valsartan Impurity 8 (CAS 137862-78-3)
- Aripiprazole Quinolinediol Impurity (CAS 1391054-74-2)
- Phenoxybenzamine EP Impurity A (CAS 902273-13-6)
- Tunodafil Impurity 2 (CAS CATO-C4X-31102)
- Ceftaroline Fosamil Impurity 24 (CAS CATO-C4X-148324)
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- 5-Amino-2-(4-(trifluoromethyl)phenyl)oxazole-4-carbonitrile (CAS 260973-63-5)
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- 3-Pyridinepropanol, 3-methanesulfonate (CAS 104536-57-4)
- Cholecystokinin Octapeptide (desulfated) (CAS 25679-24-7)
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