Famotidine Impurity 82 CAS CATO-C4X-139282
| CAS No. | CATO-C4X-139282 |
| Molecular Formula | C5H7ClN4S |
| Molecular Weight | 190.65 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Famotidine Impurity 82 (CAS CATO-C4X-139282, C5H7ClN4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Famotidine Impurity 82 (C5H7ClN4S) contains a nitrile group, sulfur-containing functionality, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H7ClN4S |
| Molecular Weight | 190.65 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Famotidine Standards
- Famotidine Impurity 02 (CAS 81152-53-6)
- Famotidine Impurity 27 (CAS 1378820-83-7)
- Famotidine Impurity 39 (CAS CATO-C4X-139239)
- Famotidine Impurity 50 (CAS 95853-51-3)
- Famotidine Impurity 78 (CAS 88068-99-9)
- Famotidine Impurity 79 (CAS CATO-C4X-139279)
- Famotidine Impurity 45 (CAS 1644079-90-2)
- Famotidine Impurity 54 (CAS CATO-C4X-139254)
Recommended Standards
- 6-chloro-3-methylimidazo[1,2-b]pyridazin-2-amine (CAS 1005785-59-0)
- (4-Chloro-1H-pyrrolo[2,3-b]pyridin-5-yl)methanol (CAS 1015610-07-7)
- p-Toluenesulfonyl Chloride (CAS 98-59-9)
- 5-Chloro-4-methoxy-1H-pyrrolo[2,3-b]pyridine (CAS 1020056-69-2)
- Bupropion Impurity 21 (CAS 2133460-42-9)
- Rabeprazole Impurity 17(See C4X-112130) (CAS CATO-C4X-112117)
- Agomelatine impurity 40 (CAS CATO-C4X-110840)
- 2-Cyano-N-(4-(diethylamino)phenyl)acetamide (CAS 29395-19-5)
- 6-(2-Cyclohexylethoxy)-3,4-dihydro-2H-naphthalen-1-one (CAS 88628-50-6)
- N-(3-Nitrophenyl)-[3,4'-bipyridin]-5-amine (CAS 821784-38-7)
- 1-(2,3,4-Trifluorophenyl)cyclopropane-1-carboxylic acid (CAS 1274900-91-2)
- 2-Bromo-1-(6-bromopyridin-2-yl)ethan-1-one (CAS 142978-11-8)
- Diosmin EP Impurity C (CAS 552-57-8)
- Stresscopin-Related Peptide (human) (CAS 348626-74-4)
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