3-Chloro-4-fluorophenylboronic Acid CAS 144432-85-9
| CAS No. | 144432-85-9 |
| Molecular Formula | C6H5BClFO2 |
| Molecular Weight | 174.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-Chloro-4-fluorophenylboronic Acid (C6H5BClFO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
3-Chloro-4-fluorophenylboronic Acid (CAS 144432-85-9) is a high-purity analytical reference standard with the molecular formula C6H5BClFO2 and a molecular weight of 174.37 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-Chloro-4-fluorophenylboronic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H5BClFO2 |
| Molecular Weight | 174.37 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 4-Chloro-2-fluorophenylboronic Acid (CAS 160591-91-3)
- (2-Chloro-6-fluorophenyl)boronic acid (CAS 313545-32-3)
- 2-Chloro-3-fluorophenylboronic Acid (CAS 871329-52-1)
- 2-Chloro-5-fluorophenylboronic Acid (CAS 444666-39-1)
- 3-Chloro-2-fluorophenylboronic Acid (CAS 352535-82-1)
- 3-Chloro-5-fluorophenylboronic Acid (CAS 328956-61-2)
- 5-Chloro-2-fluorophenylboronic acid (CAS 352535-83-2)
- (R)-(3-Chloro-2-hydroxypropyl)phosphonic acid (CAS 221627-94-7)
Recommended Standards
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- 3-(Triethylsilyl)-1-propanol (CAS 2290-36-0)
- tert-Butyl (2-chloro-5-(trifluoromethyl)pyridin-4-yl)carbamate (CAS 1956363-89-5)
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- 1-(2-Aminoethoxy)-4-methanesulfonylbenzene (CAS 1052139-16-8)
- (S)-3-(1-(tert-butoxycarbonyl)-1H-pyrazol-4-yl)-2-((tert-butoxycarbonyl)amino)propanoic acid (CAS 2387566-88-1)
- 1H-pyrazolo[4,3-b]pyridin-3-amine (CAS 202336-32-1)
- 2-Bromo-5-(3-fluoro-3-pentyl)pyridine (CAS 2090581-63-6)
- Methyl 2,3,4,5-tetrahydropyridazine-3-carboxylate (CAS 193528-27-7)
- Albuterol USP Related Compound F (CAS 1221742-55-7)
- D-Ser39-Tirzepatide (CAS CATO-CPTD788679)
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