2-Chloro-5-fluorophenylboronic Acid CAS 444666-39-1
| CAS No. | 444666-39-1 |
| Molecular Formula | C6H5BClFO2 |
| Molecular Weight | 174.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C6H5BClFO2, 2-Chloro-5-fluorophenylboronic Acid contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 174.37 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 2-Chloro-5-fluorophenylboronic Acid (CAS 444666-39-1), a certified reference material (molecular formula C6H5BClFO2, MW 174.37 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-5-fluorophenylboronic Acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H5BClFO2 |
| Molecular Weight | 174.37 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 3-Chloro-4-fluorophenylboronic Acid (CAS 144432-85-9)
- 4-Chloro-2-fluorophenylboronic Acid (CAS 160591-91-3)
- (2-Chloro-6-fluorophenyl)boronic acid (CAS 313545-32-3)
- 2-Chloro-3-fluorophenylboronic Acid (CAS 871329-52-1)
- 3-Chloro-2-fluorophenylboronic Acid (CAS 352535-82-1)
- 3-Chloro-5-fluorophenylboronic Acid (CAS 328956-61-2)
- 5-Chloro-2-fluorophenylboronic acid (CAS 352535-83-2)
- (R)-(3-Chloro-2-hydroxypropyl)phosphonic acid (CAS 221627-94-7)
Recommended Standards
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- 2,2'-Dimethyl-1,1'-bianthracene (CAS 62817-78-1)
- 3-Amino-1,2-benzoxazole-5-sulfonyl chloride (CAS 627869-92-5)
- 5-(3-Fluorophenyl)-4-methylpyridin-2-amine (CAS 1214333-48-8)
- 4-Methyl-2-(1-methylpyrrolidin-2-yl)pyridine (CAS 1352499-39-8)
- (2Z)-2-[(1E)-(Methoxyimino)methyl]-3-(2-nitrophenyl)prop-2-enenitrile (CAS 339278-33-0)
- 5-Amino-2-(4-aminophenyl)benzimidazole (CAS 7621-86-5)
- Semaglutide impurity 74 (CAS CATO-C4X-222674)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com