3-Chloro-5-fluorophenylboronic Acid CAS 328956-61-2
| CAS No. | 328956-61-2 |
| Molecular Formula | C6H5BClFO2 |
| Molecular Weight | 174.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 3-Chloro-5-fluorophenylboronic Acid (C6H5BClFO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.5, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 174.37 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
3-Chloro-5-fluorophenylboronic Acid (CAS 328956-61-2), molecular formula C6H5BClFO2 and molecular weight 174.37 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H5BClFO2 |
| Molecular Weight | 174.37 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 3-Chloro-4-fluorophenylboronic Acid (CAS 144432-85-9)
- 4-Chloro-2-fluorophenylboronic Acid (CAS 160591-91-3)
- (2-Chloro-6-fluorophenyl)boronic acid (CAS 313545-32-3)
- 2-Chloro-3-fluorophenylboronic Acid (CAS 871329-52-1)
- 2-Chloro-5-fluorophenylboronic Acid (CAS 444666-39-1)
- 3-Chloro-2-fluorophenylboronic Acid (CAS 352535-82-1)
- 5-Chloro-2-fluorophenylboronic acid (CAS 352535-83-2)
- (R)-(3-Chloro-2-hydroxypropyl)phosphonic acid (CAS 221627-94-7)
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- 4-Fluorobenzyl-α,α-d2 Chloride (CAS 1219804-18-8)
- 1-Phenyl-2-[(propan-2-yl)amino]ethan-1-ol (CAS 4164-21-0)
- Ethyl 2-(cyclohexanecarbonyl)benzoate (CAS 898792-17-1)
- Ethyl 4-isopropylbenzoate (CAS 19024-50-1)
- Tau Peptide (306-336) (Repeat 3 Domain) trifluoroacetate salt (CAS 330456-26-3)
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