Tacrolimus Impurity 43 CAS CATO-C4X-130043
| CAS No. | CATO-C4X-130043 |
| Molecular Formula | C44H69NO12 |
| Molecular Weight | 804.02 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Tacrolimus Impurity 43 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Tacrolimus Impurity 43 (CAS CATO-C4X-130043, C44H69NO12) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Tacrolimus Impurity 43 (C44H69NO12) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 804.02 g/mol, it falls into the high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C44H69NO12 |
| Molecular Weight | 804.02 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Tacrolimus Standards
- Tacrolimus (CAS 104987-11-3)
- Tacrolimus Impurity 15 (CAS CATO-C4X-130015)
- Tacrolimus Impurity 17 (CAS CATO-C4X-130017)
- Tacrolimus EP Impurity F (CAS 1393890-33-9)
- Tacrolimus EP Impurity G (CAS 144490-63-1)
- Tacrolimus Impurity 36 (CAS 131944-48-4)
- Tacrolimus Impurity 37 (CAS CATO-C4X-130037)
- Tacrolimus Impurity 38 (CAS CATO-C4X-130038)
Recommended Standards
- Tacrolimus Impurity 47 (CAS CATO-C4X-130047)
- Tacrolimus Impurity 55 (CAS CATO-C4X-130055)
- Tacrolimus Impurity 56 (CAS CATO-C4X-130056)
- Tacrolimus Impurity 57 (CAS CATO-C4X-130057)
- Naltrexone Impurity 19 (CAS 112269-62-2)
- Vortioxetine Impurity 131 HCl (CAS CATO-C4X-1056131)
- Fluvoxamine EP Impurity F Dimaleate (CAS CATO-C4X-195121)
- Angiotensin III acetate (CAS 13602-53-4(free base))
- Tert-butyl isopropyl(piperidin-4-ylmethyl)carbamate (CAS 1353986-95-4)
- (S)-2-(3-(((2,4-Diaminoquinazolin-6-yl)methyl)amino)benzamido)pentanedioic acid (CAS 29746-12-1)
- 4-Chloro-N-cyclohexyl-N-phenylbutanamide (CAS 1023536-91-5)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (5-(pyridin-4-yl)thiophen-2-yl)boronate (CAS 1402240-70-3)
- P22077 (CAS 1247819-59-5)
- Tirzepatide Impurity 9 (CAS CATO-C4X-32409)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com