Tacrolimus Impurity 36 CAS 131944-48-4
| CAS No. | 131944-48-4 |
| Molecular Formula | C44H69NO12 |
| Molecular Weight | 804.02 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Tacrolimus Impurity 36 (CAS 131944-48-4, C44H69NO12) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C44H69NO12, Tacrolimus Impurity 36 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 804.02 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Tacrolimus Impurity 36 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C44H69NO12 |
| Molecular Weight | 804.02 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Nitrogen Atoms | 1 |
Related Tacrolimus Standards
- Tacrolimus (CAS 104987-11-3)
- Tacrolimus Impurity 15 (CAS CATO-C4X-130015)
- Tacrolimus Impurity 17 (CAS CATO-C4X-130017)
- Tacrolimus EP Impurity F (CAS 1393890-33-9)
- Tacrolimus EP Impurity G (CAS 144490-63-1)
- Tacrolimus Impurity 37 (CAS CATO-C4X-130037)
- Tacrolimus Impurity 38 (CAS CATO-C4X-130038)
- Tacrolimus Impurity 43 (CAS CATO-C4X-130043)
Recommended Standards
- Tacrolimus Impurity 47 (CAS CATO-C4X-130047)
- (E/Z)-FK-506 26,28-Allylic Ester Rearrangement Impurity (CAS CATO-C4X-130012)
- Tacrolimus Impurity 55 (CAS CATO-C4X-130055)
- Tacrolimus Impurity 56 (CAS CATO-C4X-130056)
- Pazopanib Impurity 55 (CAS CATO-C4X-172555)
- Ezetimibe Ring-Opening Dehydrate Impurity (CAS 1292292-63-7)
- Olmesartan Impurity 39 (CAS 2411637-68-6)
- 5-(Bromomethyl)-1,2,3-trichlorobenzene (CAS 1261828-98-1)
- (E)-1-(2-Nitrovinyl)naphthalene (CAS 37630-26-5)
- 2,4-Bis(trifluoromethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine (CAS 911784-15-1)
- (3R)-3-amino-3-(4-chlorophenyl)propanamide hydrochloride (CAS 1384435-45-3)
- Carbazochrome Impurity 5 (CAS 2271443-87-7)
- 2-(2-Oxoimidazolidin-1-yl)acetic acid (CAS 87219-22-5)
- Semaglutide impurity 60 (CAS CATO-C4X-222660)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com