Tacrolimus Impurity 15 CAS CATO-C4X-130015
| CAS No. | CATO-C4X-130015 |
| Molecular Formula | C44H69NO12 |
| Molecular Weight | 804.02 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Tacrolimus Impurity 15 (CAS CATO-C4X-130015), a pharmacopoeial impurity reference standard (molecular formula C44H69NO12, MW 804.02 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Tacrolimus Impurity 15 (C44H69NO12) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 804.02 g/mol, it falls into the high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C44H69NO12 |
| Molecular Weight | 804.02 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Tacrolimus Standards
- Tacrolimus (CAS 104987-11-3)
- Tacrolimus Impurity 17 (CAS CATO-C4X-130017)
- Tacrolimus EP Impurity F (CAS 1393890-33-9)
- Tacrolimus EP Impurity G (CAS 144490-63-1)
- Tacrolimus Impurity 36 (CAS 131944-48-4)
- Tacrolimus Impurity 37 (CAS CATO-C4X-130037)
- Tacrolimus Impurity 38 (CAS CATO-C4X-130038)
- Tacrolimus Impurity 43 (CAS CATO-C4X-130043)
Recommended Standards
- (E/Z)-FK-506 26,28-Allylic Ester Rearrangement Impurity (CAS CATO-C4X-130012)
- [Lys5,MeLeu9,Nle10]-Neurokinin A (4-10) Fragment (CAS 137565-28-7)
- Pancreatic Polypeptide (31-36), amide, human (CAS 74012-13-8)
- Butyl 2-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]acetate (CAS 1797986-75-4)
- Peptide Impurity 40 (CAS CATO-CPTD788840)
- Clobetasol Propionate Impurity 23 (CAS CATO-C4X-159223)
- Terbinafine EP Impurity C (CAS 187540-01-8)
- 2-Hydroxy-4-amino Butanoic Acid (CAS 13477-53-7)
- 3-Chloro-5-cyclobutoxypyridazine (CAS 1346691-25-5)
- 3-Cyclopropoxy-5-ethylpyridine-2-sulfonamide (CAS 1243393-19-2)
- 6-((3-(Piperidin-1-yl)propyl)amino)quinoline-5,8-dione (CAS 35976-67-1)
- Glimepiride (CAS 93479-97-1)
- 3-Fluoro-2-(methylsulfonyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1351997-55-1)
- Mitogenic Pentapeptide (CAS 87173-03-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com