Ezetimibe Impurity N38 CAS 1510820-22-0
| CAS No. | 1510820-22-0 |
| Molecular Formula | C24H23F2NO2 |
| Molecular Weight | 395.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ezetimibe Impurity N38 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Ezetimibe Impurity N38 (CAS 1510820-22-0), a pharmacopoeial impurity reference standard (molecular formula C24H23F2NO2, MW 395.44 g/mol) used for the identification and quantification of trace impurities in APIs.
Ezetimibe Impurity N38 (C24H23F2NO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ezetimibe Impurity N38 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H23F2NO2 |
| Molecular Weight | 395.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ezetimibe Standards
- Ezetimibe Impurity 5 (CAS 1374250-07-3)
- Ezetimibe Impurity 59 (CAS CATO-C4X-109859)
- Ezetimibe Impurity 1 (CAS 204589-58-2)
- Ezetimibe Impurity 147 (3R,4R) (CAS CATO-C4X-1098147)
- Ezetimibe Desfluoroaniline analog (CAS 302781-98-2)
- Ezetimibe Impurity 22 (CAS 190595-66-5)
- Ezetimibe Impurity 66 (CAS 204589-68-4)
- Ezetimibe Impurity 63 (CAS CATO-C4X-109863)
Recommended Standards
- Icotinib-d4 (CAS 1567366-82-8)
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- 6-(Adamantan-1-yl)-3-amino-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 488795-66-0)
- Ornidazole Impurity 37 (CAS 28559-13-9)
- Lubiprostone Impurity 15 (CAS CATO-C4X-113615)
- Nefopam Impurity 3 (CAS 60725-36-2)
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- 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)benzaldehyde (CAS 1422268-45-8)
- 1-(4-Chlorophenyl)-3-[2-(methylsulfanyl)pyrimidin-4-yl]-1,4-dihydropyridazin-4-one (CAS 1263386-33-9)
- Myristoyl Pentapeptide-4 (CAS 1392416-25-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com