Tamoxifen Citrate EP Impurity D Hydrochloride(E-Isomer) CAS 15917-51-8
| CAS No. | 15917-51-8 |
| Molecular Formula | C25H27NO |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Tamoxifen Citrate EP Impurity D Hydrochloride(E-Isomer) is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Tamoxifen Citrate EP Impurity D Hydrochloride(E-Isomer) (CAS 15917-51-8) is a certified pharmaceutical impurity reference standard with the molecular formula C25H27NOHCl and a molecular weight of 393.95 g/mol.
Structurally, Tamoxifen Citrate EP Impurity D Hydrochloride(E-Isomer) (C25H27NOHCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 393.95 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Tamoxifen Citrate EP Impurity D Hydrochloride(E-Isomer) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H27NO HCl |
| Molecular Weight | 393.95 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Tamoxifen Standards
- Tamoxifen (CAS 10540-29-1)
- Tamoxifen Citrate Impurity 25 (CAS 114828-90-9)
- Tamoxifen Impurity 18 (CAS 123091-15-6)
- Tamoxifen EP Impurity A (CAS 13002-65-8)
- Tamoxifen Dimer (CAS 1346606-51-6)
- Tamoxifen Impurity 15 (CAS 157698-32-3)
- Tamoxifen EP Impurity F HCl (CAS 15917-65-4)
- Tamoxifen Citrate - Impurity D (CAS 197251-11-9)
Recommended Standards
- Nebivolol Impurity 80 (CAS CATO-C4X-196880)
- Pranoprofen Impurity 38 (CAS 53944-40-4)
- Apremilast Impurity 6 (CAS 1809170-71-5)
- Bupropion Impurity 03 (CAS 2763780-10-3)
- 1-Phenyl-5-(trifluoromethyl)pyrazole-4-carbonylchloride (CAS 175137-14-1)
- Ethyl 3-chloro-4-(((trifluoromethyl)sulfonyl)oxy)benzoate (CAS 939050-79-0)
- N-Methoxy-N,3,5-trimethylbenzamide (CAS 252199-44-3)
- 1-Chloroisoquinoline-7-carboxylic acid (CAS 730971-21-8)
- 4-(4-Pentyloxybenzoyl)isoquinoline (CAS 1187171-67-0)
- Endo-Ala35-Tirzepatide (CAS CATO-CPTD788687)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com