Lotilaner Impurity 28 CAS 1613733-77-9

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.1613733-77-9
Molecular FormulaC15H8BrCl3F3NOS
Molecular Weight493.55 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Lotilaner Impurity 28 CAS 1613733-77-9 chemical structure

Description

The occurrence of Lotilaner Impurity 28 is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

Lotilaner Impurity 28 (CAS 1613733-77-9) is a certified pharmaceutical impurity reference standard with the molecular formula C15H8BrCl3F3NOS and a molecular weight of 493.55 g/mol.

Based on its molecular formula C15H8BrCl3F3NOS, Lotilaner Impurity 28 contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 493.55 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Lotilaner Impurity 28 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC15H8BrCl3F3NOS
Molecular Weight493.55 g/mol
Purity97%+
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1993
Halogen ContentF/Cl/Br-containing
Nitrogen Atoms1
Sulfur Atoms1

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