Lotilaner Impurity 25 CAS 1613733-75-7
| CAS No. | 1613733-75-7 |
| Molecular Formula | C15H8BrCl3F3NOS |
| Molecular Weight | 493.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Lotilaner Impurity 25 (CAS 1613733-75-7, C15H8BrCl3F3NOS) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Lotilaner Impurity 25 (C15H8BrCl3F3NOS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Lotilaner Impurity 25 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H8BrCl3F3NOS |
| Molecular Weight | 493.55 g/mol |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Lotilaner Standards
- Lotilaner Impurity 28 (CAS 1613733-77-9)
- Lotilaner Impurity 5 (CAS 1613733-72-4)
- Lotilaner Impurity 16 (CAS CATO-C4X-325616)
- Lotilaner Impurity 9 (CAS CATO-C4X-32569)
- Lotilaner Impurity 26 (CAS 2758907-90-1)
- Lotilaner Impurity 3 (CAS CATO-C4X-32563)
- Lotilaner Impurity 6 (CAS CATO-C4X-32566)
- Lotilaner Impurity 19 (CAS CATO-C4X-325619)
Recommended Standards
- Fmoc-D-Tyr(Bzl)-OH (CAS 138775-48-1)
- N-Fmoc-L-tyrosine Benzyl Ester (CAS 82911-77-1)
- Fmoc-Tyr(Bzl)-OH (CAS 71989-40-7)
- MOCPAC (CAS 787549-26-2)
- Lefamulinum Impurity 45 (CAS CATO-C4X-304745)
- Glumetinib Impurity 9 (CAS CATO-C4X-32599)
- Levofloxacin Impurity 32 (CAS 1329833-82-0)
- Tert-butyl (3aR,6aS)-hexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate (CAS 926276-08-6)
- N-(4-Bromophenyl)-2-methylbenzamide (CAS 66569-03-7)
- 5-(m-Tolylamino)pyrimidine-2,4(1H,3H)-dione (CAS 4878-46-0)
- 2-Methoxy-4-methylpyridin-3-amine hydrochloride (CAS 180087-79-0)
- 2,3,3',4,4',6-Hexabromodiphenyl ether (BDE-158) Solution (CAS 446255-09-0)
- 3-([(tert-Butyldimethylsilyl)oxy]methyl)piperidine (CAS 876147-50-1)
- Semaglutide impurity 87 (CAS CATO-C4X-222687)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com