Lotilaner Impurity 5 CAS 1613733-72-4
| CAS No. | 1613733-72-4 |
| Molecular Formula | C15H7BrCl3F3OS |
| Molecular Weight | 478.54 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Lotilaner Impurity 5 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Lotilaner Impurity 5 (CAS 1613733-72-4, C15H7BrCl3F3OS) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Lotilaner Impurity 5 (C15H7BrCl3F3OS) contains sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C15H7BrCl3F3OS |
| Molecular Weight | 478.54 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F/Cl/Br-containing |
| Sulfur Atoms | 1 |
Related Lotilaner Standards
- Lotilaner Impurity 16 (CAS CATO-C4X-325616)
- Lotilaner Impurity 9 (CAS CATO-C4X-32569)
- Lotilaner Impurity 26 (CAS 2758907-90-1)
- Lotilaner Impurity 3 (CAS CATO-C4X-32563)
- Lotilaner Impurity 6 (CAS CATO-C4X-32566)
- Lotilaner Impurity 19 (CAS CATO-C4X-325619)
- Lotilaner Impurity 25 (CAS 1613733-75-7)
- Lotilaner Impurity 28 (CAS 1613733-77-9)
Recommended Standards
- Abemaciclib Impurity 42 (CAS 1231930-57-6)
- Prusogliptin Impurity 10 (CAS CATO-C4X-328410)
- Finerenone Impurity 82 (CAS CATO-C4X-288082)
- Ensifentrine impurity 11 (CAS CATO-C4X-335311)
- Encorafenib Impurity 13 (CAS CATO-C4X-324913)
- Metamizole Monohydrate EP Impurity E (CAS 117-38-4(free base))
- Vinorelbine EP Impurity F Iodide (CAS CATO-C4X-26427)
- tert-Butyl 3-(1-aminoethyl)morpholine-4-carboxylate (CAS 1508368-16-8)
- tert-Butyl (2R)-2-(aminomethyl)-2-methylpyrrolidine-1-carboxylate (CAS 1407997-78-7)
- Itx5061 (CAS 1252679-52-9)
- 5-(Dimethoxymethyl)-5-propylimidazolidine-2,4-dione (CAS 7146-47-6)
- Cyclo(-Glu-Glu) (CAS 16691-00-2)
- 3-(2-Methylphenyl)cyclopentanone (CAS 1181643-89-9)
- (Ser(PO3H2)202,Thr(PO3H2)205)-Tau Peptide (194-213) trifluoroacetate salt (CAS 2022956-55-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com