Roflumilast USP Related Compound D CAS 162401-62-9

Description

Compared with other compounds in its class, the molecular weight of 258.22 g/mol gives Roflumilast USP Related Compound D distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Roflumilast USP Related Compound D (CAS 162401-62-9), molecular formula C12H12F2O4 and molecular weight 258.22 g/mol, is a CATO reference standard with documented purity and traceability.

Roflumilast USP Related Compound D (C12H12F2O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), Roflumilast USP Related Compound D meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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