Levothyroxine Impurity 58 CAS 176258-87-0
| CAS No. | 176258-87-0 |
| Molecular Formula | C14H11I3O2 |
| Molecular Weight | 591.95 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Levothyroxine Impurity 58 (CAS 176258-87-0) is a high-purity analytical reference standard with the molecular formula C14H11I3O2 and a molecular weight of 591.95 g/mol.
Based on its molecular formula C14H11I3O2, Levothyroxine Impurity 58 contains a carboxylic acid group, a hydroxyl group, an ether linkage, iodine substitution, a polycyclic aromatic system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 591.95 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H11I3O2 |
| Molecular Weight | 591.95 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | I-containing |
Related Levothyroxine Standards
- Levothyroxine Impurity 42 (CAS 4618-45-5)
- Levothyroxine Impurity 16 (CAS 92905-78-7)
- Levothyroxine EP Impurity C (CAS 51-24-1)
- Levothyroxine Impurity 14 (CAS 3914-31-6)
- Levothyroxine Impurity 17 (CAS 51-26-3)
- Levothyroxine Impurity 37 (CAS 94345-95-6)
- Levothyroxine EP Impurity A (CAS 6893-02-3)
- Levothyroxine EP Impurity K (CAS 5817-39-0)
Recommended Standards
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