Lenvatinib Impurity 25（Phenyl Chloroformate） CAS 1885-14-9
| CAS No. | 1885-14-9 |
| Molecular Formula | C7H5ClO2 |
| Molecular Weight | 156.57 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Lenvatinib Impurity 25（Phenyl Chloroformate） meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Lenvatinib Impurity 25（Phenyl Chloroformate） (CAS 1885-14-9, C7H5ClO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C7H5ClO2, Lenvatinib Impurity 25（Phenyl Chloroformate） contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 156.57 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C7H5ClO2 |
| Molecular Weight | 156.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >90% |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
Related Lenvatinib Standards
- Lenvatinib Impurity 69 (CAS 40140-91-8)
- Lenvatinib Impurity 97 (CAS 75955-30-5)
- Lenvatinib Impurity 103 (CAS 2486-80-8)
- Lenvatinib Impurity 83 (CAS 56766-77-9)
- Lenvatinib Impurity 98 (CAS CATO-C4X-114098)
- Lenvatinib Impurity 130 (CAS 16026-77-0)
- Lenvatinib Impurity 132 (CAS 56962-01-7)
- Lenvatinib Impurity 33 (CAS 3964-52-1)
Recommended Standards
- Sildenafil Impurity 42 (CAS 1441-87-8)
- Bupropion Impurity 49 (CAS 535-80-8)
- Dronedarone Impurity 56 (CAS 28141-24-4)
- Mesalazine EP Impurity L (CAS 118-91-2)
- Amoxicillin EP impurity D1-2 (CAS 93302-27-3)
- Niraparib Impurity 53 (CAS 1584236-54-3)
- Norethisterone Acetate EP Impurity E (CAS 66964-58-7)
- Renin Substrate 1 trifluoroacetate salt (CAS 791068-69-4)
- ((2S,4R)-4-Methoxy-1-methylpyrrolidin-2-yl)methanol (CAS 1842337-34-1)
- Poly(methacrylic acid) (CAS 25087-26-7)
- 4-Chloro-2-(methylthio)-5-thiazolecarbonitrile (CAS 120891-11-4)
- 2-Ethoxy-3-phenylquinazolin-4(3H)-one (CAS 734-62-3)
- n-(4-(2-((2-Methoxyethyl)amino)ethyl)phenyl)acetamide (CAS 1310258-21-9)
- Semaglutide Impurity 121 X Sodium Salt (CAS CATO-C4X-2226121)
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