Nilotinib N-Oxide (Imidazole N-Oxide) CAS 2139382-75-3
| CAS No. | 2139382-75-3 |
| Molecular Formula | C28H22F3N7O2 |
| Molecular Weight | 545.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Nilotinib N-Oxide (Imidazole N-Oxide).
Nilotinib N-Oxide (Imidazole N-Oxide) (CAS 2139382-75-3), molecular formula C28H22F3N7O2 and molecular weight 545.52 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Nilotinib N-Oxide (Imidazole N-Oxide) (C28H22F3N7O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Nilotinib N-Oxide (Imidazole N-Oxide) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C28H22F3N7O2 |
| Molecular Weight | 545.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 7 |
Related Nilotinib Standards
- Nilotinib N-Oxide (CAS 1246817-85-5)
- Nilotinib Impurity 47 (CAS 1807606-80-9)
- Nilotinib Impurity 52 (CAS CATO-C4X-125652)
- Nilotinib Impurity 53 (CAS CATO-C4X-125653)
- Nilotinib Impurity 11 (CAS CATO-C4X-125611)
- Nilotinib Hydrochloride Monohydrate EP Impurity F (CAS 2119583-24-1)
- Nilotinib Impurity 43 (CAS CATO-C4X-125643)
- Nilotinib-d6 (CAS 1268356-17-7)
Recommended Standards
- 2-Nitrophenyl β-D-galactopyranoside-6-phosphate cyclohexylammonium salt (CAS 25405-62-3)
- Elagolix Impurity 88 (CAS CATO-C4X-206888)
- S-Elagolix Impurity 6 (CAS 2756307-50-1)
- N-[3-[[2-[[4-[[1-(2-Fluoroethyl)-3-azetidinyl]amino]-2-methoxyphenyl]amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]phenyl]-2-propenamide (CAS 1375465-09-0)
- ethyl 3,4-dihydro-2H-pyran-2-carboxylate (CAS 83568-11-0)
- <I>N </I>-Fluorobenzenesulfonimide (CAS 133745-75-2)
- tert-Butyl (2-bromo-3-chlorophenyl)carbamate (CAS 1463053-89-5)
- Benzyl N-[3-(tetramethyl-1,3,2-dioxaborolan-2-yl)propyl]carbamate (CAS 2377607-42-4)
- 8-(Piperidin-3-yl)-9H-purine (CAS 1499818-35-7)
- 2-(Thiophen-2-yl)pyrimidine-5-carbonitrile (CAS 926921-77-9)
- (3-Amino-5-cyclopropylphenyl)boronic acid (CAS 2225169-81-1)
- tert-Butyl ((S)-1-((S)-oxiran-2-yl)-2-phenylethyl)carbamate (CAS 286019-82-7)
- (4-(Ethylsulfonamidomethyl)phenyl)boronic acid (CAS 1509931-31-0)
- Peptide T (CAS 106362-32-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com