Cyclophosphamide Impurity 19 CAS 22089-17-4

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.22089-17-4
Molecular FormulaC8H17Cl2N2O2P
Molecular Weight275.11 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Cyclophosphamide Impurity 19 CAS 22089-17-4 chemical structure

Description

CATO supplies Cyclophosphamide Impurity 19 (CAS 22089-17-4), a pharmacopoeial impurity reference standard (molecular formula C8H17Cl2N2O2P, MW 275.11 g/mol) used for the identification and quantification of trace impurities in APIs.

Based on its molecular formula C8H17Cl2N2O2P, Cyclophosphamide Impurity 19 contains an amide group, organophosphorus functionality, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic functional-group stretching vibrations in infrared spectroscopy. The molecular weight of 275.11 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H17Cl2N2O2P
Molecular Weight275.11 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)0.5
CAS Registry Year (est.)1963
Halogen ContentCl-containing
Nitrogen Atoms2

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