Cyclophosphamide Impurity 9 CAS 40277-05-2
| CAS No. | 40277-05-2 |
| Molecular Formula | C7H15Cl2N2O3P |
| Molecular Weight | 277.09 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Cyclophosphamide Impurity 9 (C7H15Cl2N2O3P) contains an amide group, a phosphonate group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Cyclophosphamide Impurity 9 (CAS 40277-05-2) is a certified pharmaceutical impurity reference standard with the molecular formula C7H15Cl2N2O3P and a molecular weight of 277.09 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Cyclophosphamide Impurity 9 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H15Cl2N2O3P |
| Molecular Weight | 277.09 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 0.5 |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Cyclophosphamide Standards
- Cyclophosphamide impurity 01 (CAS 35144-64-0)
- Cyclophosphamide Impurity 12 (CAS 78149-83-4)
- Cyclophosphamide Impurity 19 (CAS 22089-17-4)
- Cyclophosphamide Impurity 22 (CAS 3308-51-8)
- Cyclophosphamide impurity 32 (CAS CATO-C4X-230632)
- 4-Oxo Cyclophosphamide (CAS 27046-19-1)
- Cyclophosphamide impurity 40 (CAS CATO-C4X-230640)
- Cyclophosphamide Impurity 12 (CAS CATO-C4X-230612)
Recommended Standards
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com