Diclofenac sodium impurity 65 CAS 220991-19-5

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.220991-19-5
Molecular FormulaC15H12Cl2NO2
Molecular WeightN/A
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Diclofenac sodium impurity 65 CAS 220991-19-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 332.16 g/mol gives Diclofenac sodium impurity 65 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Diclofenac sodium impurity 65 (CAS 220991-19-5), a pharmacopoeial impurity reference standard (molecular formula C15H12Cl2NO2Na, MW 332.16 g/mol) used for the identification and quantification of trace impurities in APIs.

Owing to a salt form, a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Diclofenac sodium impurity 65 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 332.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Diclofenac sodium impurity 65 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC15H12Cl2NO2 Na
Molecular Weight332.16 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2020
Halogen ContentCl-containing
Nitrogen Atoms1

Related Diclofenac Standards

Recommended Standards

Why CATO?