Hydrochlorothiazide Impurity 6 CAS 23141-82-4
| CAS No. | 23141-82-4 |
| Molecular Formula | C7H9N3O4S2 |
| Molecular Weight | 263.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Hydrochlorothiazide Impurity 6 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Hydrochlorothiazide Impurity 6 (CAS 23141-82-4, C7H9N3O4S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C7H9N3O4S2, Hydrochlorothiazide Impurity 6 contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 263.29 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C7H9N3O4S2 |
| Molecular Weight | 263.29 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related Hydrochlorothiazide Standards
- Hydrochlorothiazide Impurity 7 (CAS CATO-C4X-11777)
- Hydrochlorothiazide Impurity 19 (CAS 79271-56-0)
- Hydrochlorothiazide Impurity 9 (CAS 364-96-5)
- Hydrochlorothiazide Impurity 15 (CAS 23141-75-5)
- Hydrochlorothiazide Impurity 19 (CAS 85119-88-6)
- Hydrochlorothiazide Impurity 20 (CAS 82205-98-9)
- Hydrochlorothiazide EP Impurity B (CAS 121-30-2)
- Hydrochlorothiazide impurity 44 (CAS CATO-C4X-117744)
Recommended Standards
- Salbutamol Impurity 97 (CAS 53942-75-9)
- Aripiprazole impurity 80 (CAS CATO-C4X-100880)
- Bisoprolol EP Impurity T (CAS 1173203-26-3)
- Trimethoprim Impurity 6 (CAS 7520-69-6)
- Amorolfine EP Impurity F (CAS 106614-66-8)
- Pimavanserin Impurity 17 (CAS CATO-C4X-193817)
- Enzalutamide Impurity 44 (CAS 24115-24-0)
- D-Glutamic-2,3,3,4,4-d5 Acid (CAS 14341-88-9)
- (2-Fluoro-3-(4-methylpiperidine-1-carbonyl)phenyl)boronic acid (CAS 2096334-32-4)
- [(5-Bromopentyl)oxy](tert-butyl)dimethylsilane (CAS 85514-43-8)
- 7-Carboxy-9(11)Δ-canrenone(Mixture of diastereomers) (CAS 95716-74-8)
- 2,2-DIMETHYL-2H-BENZO[B][1,4]THIAZIN-3(4H)-ONE (CAS 90921-53-2)
- N-(thiazol-2-ylmethyl)propan-2-amine (CAS 792185-36-5)
- Tetrapeptide-30/Tegopep (CAS 1036207-61-0)
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