Hydrochlorothiazide Impurity 15 CAS 23141-75-5

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.23141-75-5
Molecular FormulaC7H7N3O4S2
Molecular Weight261.28 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Hydrochlorothiazide Impurity 15 CAS 23141-75-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 261.28 g/mol gives Hydrochlorothiazide Impurity 15 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Hydrochlorothiazide Impurity 15 (CAS 23141-75-5), a pharmacopoeial impurity reference standard (molecular formula C7H7N3O4S2, MW 261.28 g/mol) used for the identification and quantification of trace impurities in APIs.

Structurally, Hydrochlorothiazide Impurity 15 (C7H7N3O4S2) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 261.28 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Hydrochlorothiazide Impurity 15 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC7H7N3O4S2
Molecular Weight261.28 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1963
Nitrogen Atoms3
Sulfur Atoms2

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