Hydrochlorothiazide Impurity 19 CAS 79271-56-0
| CAS No. | 79271-56-0 |
| Molecular Formula | C7H15F3O3SSi |
| Molecular Weight | 264.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Hydrochlorothiazide Impurity 19 (CAS 79271-56-0) is a certified pharmaceutical impurity reference standard with the molecular formula C7H15F3O3SSi and a molecular weight of 264.34 g/mol.
Structurally, Hydrochlorothiazide Impurity 19 (C7H15F3O3SSi) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of -1.0, corresponding to approximately 0 ring(s) or double-bond equivalent(s). With a molecular weight of 264.34 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C7H15F3O3SSi |
| Molecular Weight | 264.34 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | -1.0 |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Hydrochlorothiazide Standards
- Hydrochlorothiazide Impurity 9 (CAS 364-96-5)
- Hydrochlorothiazide Impurity 6 (CAS 23141-82-4)
- Hydrochlorothiazide Impurity 7 (CAS CATO-C4X-11777)
- Hydrochlorothiazide Impurity 19 (CAS 85119-88-6)
- Hydrochlorothiazide Impurity 15 (CAS 23141-75-5)
- Hydrochlorothiazide Impurity 20 (CAS 82205-98-9)
- Hydrochlorothiazide EP Impurity B (CAS 121-30-2)
- Hydrochlorothiazide impurity 44 (CAS CATO-C4X-117744)
Recommended Standards
- 2,4-DIBROMOBUTANOYL CHLORIDE 2,4-DIBROMOBUTYRYL CHLORIDE 82820-87-9 BC004825 BUTANOYL CHLORIDE, 2,4-DIBROMO- (CAS 82820-87-9)
- Pimavanserin Impurity 38 (CAS CATO-C4X-193838)
- Trifluoro-methanesulfonic acid butyldimethylsilyl ester (CAS 301338-11-4)
- Abemaciclib Impurity 35 (CAS CATO-C4X-293735)
- Sildenafil Impurity 64 (CAS 59023-32-4)
- Paroxetine EP Impurity G HCl (CAS 1012886-75-7)
- Haloperidol Impurity 13 (CAS CATO-C4X-146113)
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- 2-Amino-3-(4-methoxy-3-(trifluoromethoxy)phenyl)propanoic acid (CAS 1259979-50-4)
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- 3-Cyclopropoxy-2-ethyl-4-isopropoxypyridine (CAS 1243310-58-8)
- D-[Ser]8-Semaglutide (CAS CATO-CPTD788632)
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