Naproxen EP Impurity G (R-Naproxen) CAS 23979-41-1
| CAS No. | 23979-41-1 |
| Molecular Formula | C14H14O3 |
| Molecular Weight | 230.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Naproxen EP Impurity G (R-Naproxen) (CAS 23979-41-1, C14H14O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C14H14O3, Naproxen EP Impurity G (R-Naproxen) contains a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 230.26 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H14O3 |
| Molecular Weight | 230.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
Related Naproxen Standards
- Naproxen Impurity 26 (CAS 23981-80-8)
- Naproxen (CAS 22204-53-1)
- Naproxen Impurity 41 (CAS CATO-C4X-170841)
- Naproxen Impurity 42 (CAS CATO-C4X-170842)
- Naproxen Impurity 7 (CAS CATO-C4X-17087)
- Naproxen Dehydro Impurity (CAS 27602-79-5)
- (S)-Naproxen-d3 (CAS 1094102-82-5)
- rac-Naproxen-13C,d3 (CAS 1216704-11-8)
Recommended Standards
- （R)-Etomidate EP Impurity B (CAS 61045-91-8)
- Tryptophan EP Impurity I (CAS 5470-37-1)
- Ozagrel Impurity 28 (CAS 103549-17-3)
- Bisoprolol Impurity 93 (CAS 2350-43-8)
- Carfilzomib Impurity 39 (CAS 875309-82-3)
- Baricitinib Impurity N2 (CAS 941685-27-4)
- Roflumilast Impurity 37 (CAS CATO-C4X-108437)
- 5-Chloro-6-methoxy-2,3-dihydro-1H-inden-1-one (CAS 344305-70-0)
- 5-Propylisoxazol-3(2H)-one (CAS 10004-46-3)
- 1,6,8-Trichlorodibenzo[b,d]furan (CAS 82911-59-9)
- N-Benzyl-N-(6-fluorobenzo[d]thiazol-2-yl)butyramide (CAS 899735-02-5)
- 1-(2-Chloropyridin-4-yl)ethan-1-amine (CAS 1060811-99-5)
- (4-(Difluoromethoxy)-5-fluoropyridin-2-yl)methanamine hydrochloride (CAS 2231675-51-5)
- Semaglutide impurity 60 (CAS CATO-C4X-222660)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com