Trazodone Hydrochloride EP Impurity G CAS 2470441-00-8
| CAS No. | 2470441-00-8 |
| Molecular Formula | C17H27ClN2O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Trazodone Hydrochloride EP Impurity G (CAS 2470441-00-8) is a certified pharmaceutical impurity reference standard with the molecular formula C17H27ClN2OHCl and a molecular weight of 347.32 g/mol.
The molecular framework of Trazodone Hydrochloride EP Impurity G (C17H27ClN2OHCl) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Trazodone Hydrochloride EP Impurity G under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H27ClN2O HCl |
| Molecular Weight | 347.32 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Trazodone Standards
- Trazodone Impurity N13 (CAS 101364-27-6)
- Trazodone D6 (CAS 1181578-48-2)
- Trazodone-d6 Hydrochloride (CAS 1181578-71-1)
- Trazodone Hydrochloride EP Impurity C (CAS 1263278-77-8)
- Trazodone Impurity 4 (CAS 1263278-79-0)
- Trazodone EP Impurity D HCl (CAS 1263278-80-3)
- Trazodone Hydrochloride EP Impurity J (CAS 1263358-12-8)
- Trazodone EP Impurity D (CAS 1263358-13-9)
Recommended Standards
- Cilastatin EP Impurity A(Mixture Of Diastereomers) (CAS CATO-C4X-19601)
- 7-ACCA Impurity 4 (CAS CATO-C4X-23134)
- Latamoxef impurity 47 (CAS CATO-C4X-179847)
- 7-Chloro-3,8-dimethyl-2-(4-methylphenyl)quinoline-4-carbonyl chloride (CAS 1160257-02-2)
- 2-((1R,2S,4R)-bicyclo[2.2.1]Hept-5-en-2-yl)acetic acid (CAS 1092689-34-3)
- (2-Isocyanoethyl)-benzene (CAS 59795-89-0)
- (2-((4-Methoxybenzyl)oxy)pyrimidin-5-yl)boronic acid (CAS 1217500-72-5)
- 1-(2-Methoxyphenyl)-1H-imidazole-2-thiol (CAS 51581-48-7)
- 2,4-Dimethylpiperidine Hydrochloride (CAS 91846-47-8)
- Tirzepatide Impurity 13 (CAS CATO-C4X-324013)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com