Baricitinib Impurity 25 HCl CAS 2497340-56-2
| CAS No. | 2497340-56-2 |
| Molecular Formula | C14H13N7 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Baricitinib Impurity 25 HCl (CAS 2497340-56-2, C14H13N7HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Baricitinib Impurity 25 HCl (C14H13N7HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Baricitinib Impurity 25 HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H13N7 HCl |
| Molecular Weight | 315.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 7 |
Related Baricitinib Standards
- Baricitinib Impurity 21 (CAS 1024120-52-2)
- Baricitinib Impurity 14 (CAS 1029716-44-6)
- Baricitinib Impurity 23 (CAS 1146629-75-5)
- Baricitinib Impurity 39 (CAS 1146629-76-6)
- Baricitinib Impurity 42 (CAS 1146629-77-7)
- Baricitinib Impurity 18 (CAS 1153949-11-1)
- Baricitinib Impurity N5 (CAS 1153949-15-5)
- Baricitinib (CAS 1187594-09-7)
Recommended Standards
- Linaprazan Impurity 14 (CAS CATO-C4X-348614)
- Sitagliptin Impurity 86 (CAS 1246961-45-4)
- Vericiguat Impurity 15 (CAS 1361232-73-6)
- 2-((5-Amino-6-chloropyrimidin-4-yl)thio)acetonitrile (CAS 19144-84-4)
- 4-Acetoxy-3-iodobenzoic acid (CAS 190067-59-5)
- (6-Amino-9H-purin-9-yl)methanol (CAS 95121-23-6)
- 2-(2-((5-Amino-1H-1,2,4-triazol-3-yl)thio)ethyl)isoindoline-1,3-dione (CAS 728901-60-8)
- Glibenclamide EP Impurity B (CAS 21165-77-5)
- 4-(3-Chlorophenyl)-5-((o-tolyloxy)methyl)-4H-1,2,4-triazole-3-thiol (CAS 483292-99-5)
- D-Lys16-Tirzepatide (CAS CATO-CPTD788918)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com