Ivacaftor Impurity 9 CAS 26892-90-0
| CAS No. | 26892-90-0 |
| Molecular Formula | C12H11NO3 |
| Molecular Weight | 217.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ivacaftor Impurity 9 is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Ivacaftor Impurity 9 (CAS 26892-90-0) is a certified pharmaceutical impurity reference standard with the molecular formula C12H11NO3 and a molecular weight of 217.22 g/mol.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Ivacaftor Impurity 9 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 217.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Ivacaftor Impurity 9 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H11NO3 |
| Molecular Weight | 217.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Nitrogen Atoms | 1 |
Related Ivacaftor Standards
- Ivacaftor Impurity 7 (CAS 52980-28-6)
- Ivacaftor impurity 17 (CAS CATO-C4X-296417)
- Ivacaftor Impurity 10 (CAS 873055-58-4)
- Ivacaftor Impurity 12 (CAS CATO-C4X-296412)
- Ivacaftor Impurity 11 (CAS 13721-01-2)
- Ivacaftor Impurity 3 (CAS 873055-57-3)
- Ivacaftor Impurity 14 (CAS 54535-22-7)
- Ivacaftor Impurity 13 (CAS 529-37-3)
Recommended Standards
- (S)-2-Acetamido-5-ureidopentanoic Acid (CAS 33965-42-3)
- Penicillamine Impurity 1 (CAS 856846-79-2)
- 4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one (CAS 15646-46-5)
- Antipyrine Impurity 2 (CAS 885-11-0)
- Rebamipide Impurity 68 (CAS CATO-C4X-152368)
- Fluconazole Impurity 27 (CAS CATO-C4X-101927)
- Celiprolol EP Impurity G (CAS 56980-98-4)
- 2-(Dimethoxymethyl)-1,6-naphthyridine (CAS 386715-36-2)
- 2-(pyridin-3-yl)piperazine (CAS 111781-56-7)
- 5-Methoxy-2,3-dihydro-1-benzofuran-7-carboxylic acid (CAS 35700-52-8)
- Methyl 8-bromo-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxylate (CAS 1189815-76-6)
- 6-Amino-1-(2,2,2-trifluoroethyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 1021143-59-8)
- 2-(pyridazin-3-yl)ethan-1-ol (CAS 101479-62-3)
- Des-Ile27-Tirzepatide (CAS CATO-CPTD788946)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com