Berberine Impurity 11 Chloride CAS 30044-78-1
| CAS No. | 30044-78-1 |
| Molecular Formula | C19H14NO4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Berberine Impurity 11 Chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Berberine Impurity 11 Chloride (CAS 30044-78-1), a pharmacopoeial impurity reference standard (molecular formula C19H14NO4Cl, MW 355.77 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Berberine Impurity 11 Chloride (C19H14NO4Cl) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C19H14NO4 Cl |
| Molecular Weight | 355.77 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Berberine Standards
- Berberine Impurity 33 (CAS 100101-07-3)
- Berberine Impurity 15 Chloride (CAS 1186107-72-1)
- Berberine Chloride hydrate (CAS 141433-60-5)
- Berberine Impurity 31 (CAS 17388-19-1)
- Berberine Impurity 14 (CAS 2043361-62-0)
- Berberine (CAS 2086-83-1)
- Berberine Impurity 16 Chloride (CAS 2363741-22-2)
- Berberine Impurity 29 (CAS 2375597-30-9)
Recommended Standards
- Entacapone EP Impurity E (CAS 7659-29-2)
- Ezetimibe Impurity 17(SCH59566) (CAS 1296129-15-1)
- Lifitegrast Impurity 137 (CAS CATO-C4X-2409137)
- 1H-pyrazolo[4,3-b]pyridin-3-ylmethanol (CAS 1785566-87-1)
- 4-Phenylquinoline (CAS 605-03-8)
- 13569-75-0 Chromium iodide (CrI3) Chromium triiodide Chromium iodide EINECS 236-991-3 (CAS 13569-75-0)
- 2-((Dimethylamino)((5-(trifluoromethyl)pyridin-2-yl)thio)methylene)malononitrile (CAS 339022-95-6)
- Tert-butyl 3,3-difluoro-4-methylpiperidine-1-carboxylate (CAS 1373502-94-3)
- 1-(2-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperidine (CAS 2096341-25-0)
- D-[Thr]7-Liraglutide (CAS CATO-C4X-199237)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com