Paracetamol EP Impurity G CAS 34523-34-7
| CAS No. | 34523-34-7 |
| Molecular Formula | C8H9NO2 |
| Molecular Weight | 151.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Paracetamol EP Impurity G.
Paracetamol EP Impurity G (CAS 34523-34-7) is a certified pharmaceutical impurity reference standard with the molecular formula C8H9NO2 and a molecular weight of 151.16 g/mol.
Paracetamol EP Impurity G (C8H9NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Paracetamol EP Impurity G meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H9NO2 |
| Molecular Weight | 151.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Nitrogen Atoms | 1 |
Related Paracetamol Standards
- Paracetamol EP Impurity A (CAS 614-80-2)
- Paracetamol (CAS 103-90-2)
- Paracetamol EP Impurity B (CAS 1693-37-4)
- Paracetamol EP Impurity I (CAS 118-93-4)
- Paracetamol EP Impurity E (CAS 99-93-4)
- Paracetamol EP Impurity J (CAS 539-03-7)
- Paracetamol EP Impurity C (CAS 3964-54-3)
- Paracetamol EP Impurity K (CAS 123-30-8)
Recommended Standards
- Nilotinib Hydrochloride Monohydrate EP Impurity C (CAS 2458-12-0)
- Sorafenib impurity 66 (CAS CATO-C4X-112466)
- Cefaclor EP Impurity A (CAS 875-74-1)
- Milrinone Impurity 24 (CAS CATO-C4X-109124)
- Ropinirole Hydrochloride EP Impurity C (CAS 784110-47-0)
- Cefodizime Impurity 18 (CAS 66340-86-1)
- Palbociclib Impurity 208 (CAS 120613-50-5)
- Ethyl 2-chloro-5-nitrobenzoate (CAS 16588-17-3)
- 1-Cyclopropyl-2-iodo-3-methoxy-5-(trifluoromethyl)benzene (CAS 2913573-44-9)
- 2-(8-Chloro-4-oxoquinolin-1(4H)-yl)acetonitrile (CAS 1169961-43-6)
- [3-Fluoro-4-(oxan-4-ylmethoxy)phenyl]methanamine hydrochloride (CAS 1402232-74-9)
- 3-(Methylthio)propionyl Chloride (CAS 7031-23-4)
- (2-(6-Hydroxypyridin-3-yl)phenyl)(pyrrolidin-3-yl)methanone (CAS 1261896-01-8)
- Tirzepatide Impurity 21 X TFA Salt (CAS CATO-C4X-324021)
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