Paracetamol EP Impurity A CAS 614-80-2
| CAS No. | 614-80-2 |
| Molecular Formula | C8H9NO2 |
| Molecular Weight | 151.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Paracetamol EP Impurity A under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Paracetamol EP Impurity A (CAS 614-80-2) is a certified pharmaceutical impurity reference standard with the molecular formula C8H9NO2 and a molecular weight of 151.16 g/mol.
Paracetamol EP Impurity A (C8H9NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C8H9NO2 |
| Molecular Weight | 151.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Paracetamol Standards
- Paracetamol EP Impurity G (CAS 34523-34-7)
- Paracetamol (CAS 103-90-2)
- Paracetamol EP Impurity B (CAS 1693-37-4)
- Paracetamol EP Impurity I (CAS 118-93-4)
- Paracetamol EP Impurity E (CAS 99-93-4)
- Paracetamol EP Impurity J (CAS 539-03-7)
- Paracetamol EP Impurity C (CAS 3964-54-3)
- Paracetamol EP Impurity K (CAS 123-30-8)
Recommended Standards
- Sorafenib impurity 66 (CAS CATO-C4X-112466)
- Milrinone Impurity 24 (CAS CATO-C4X-109124)
- Nilotinib Hydrochloride Monohydrate EP Impurity C (CAS 2458-12-0)
- Etoricoxib impurity 64 (CAS 65719-09-7)
- Tolbutamide EP Impurity B (CAS 1694-06-0)
- Sorafenib EP Impurity G (CAS 18585-06-3)
- Ibutilide Impurity 8 (CAS CATO-C4X-21108)
- [3-(3,5-Dimethyl-1H-pyrazol-1-yl)-benzyl]methylamine dihydrochloride (CAS 1185293-07-5)
- 5-(N,N-Dimethylsulfamoyl)-1-methyl-1H-indole-3-carboxylic acid (CAS 120729-92-2)
- 5,10,15,20-Tetraphenylporphyrinato cobalt(III) (CAS 38414-01-6)
- N-(Pyridin-2-yl)pyrimidine-5-carboximidamide (CAS 90844-40-9)
- DIVINYL-PROTOCHLOROPHYLLIDE (CAS 18433-30-2)
- 3-(2-Chlorophenyl)-4-phenyl-5-(propylthio)-4H-1,2,4-triazole (CAS 81518-32-3)
- Tetrapeptide-3 (CAS 827306-97-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com