Paracetamol EP Impurity E CAS 99-93-4

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.99-93-4
Molecular FormulaC8H8O2
Molecular Weight136.15 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Paracetamol EP Impurity E CAS 99-93-4 chemical structure

Description

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a process- or degradation-related impurity, Paracetamol EP Impurity E (CAS 99-93-4, C8H8O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Paracetamol EP Impurity E (C8H8O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

CATO manufactures Paracetamol EP Impurity E under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC8H8O2
Molecular Weight136.15 g/mol
Purity>95%
StorageStore at 2-8°C
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957

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