| CAS No. | 3469-69-0 |
| Molecular Formula | C3H3IN2 |
| Molecular Weight | 193.97 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Compared with other compounds in its class, the molecular weight of 193.97 g/mol gives Crizotinib impurity 22 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Crizotinib impurity 22 (CAS 3469-69-0) is a certified pharmaceutical impurity reference standard with the molecular formula C3H3IN2 and a molecular weight of 193.97 g/mol.
Based on its molecular formula C3H3IN2, Crizotinib impurity 22 contains a nitrile group, iodine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 193.97 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Crizotinib impurity 22 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
| Molecular Formula | C3H3IN2 |
| Molecular Weight | 193.97 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 2 |