Sertraline Impurity 45 CAS CATO-C4X-134445
| CAS No. | CATO-C4X-134445 |
| Molecular Formula | C17H18ClN |
| Molecular Weight | 271.78 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Sertraline Impurity 45 (C17H18ClN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a process- or degradation-related impurity, Sertraline Impurity 45 (CAS CATO-C4X-134445, C17H18ClN) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Sertraline Impurity 45 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H18ClN |
| Molecular Weight | 271.78 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Sertraline Standards
- Sertraline - Impurity C (Freebase) (CAS 107538-91-0)
- Sertraline EP Impurity D (1S, 4S-Isomer) (CAS 871838-58-3)
- Sertraline Impurity 46 (CAS CATO-C4X-134446)
- Sertraline Impurity 71 (CAS CATO-C4X-134471)
- Sertraline Impurity 75 (CAS CATO-C4X-134475)
- Sertraline Impurity 29 (CAS 36159-73-6)
- Sertraline Impurity 69 (CAS CATO-C4X-134469)
- Sertraline Impurity 66 (CAS CATO-C4X-134466)
Recommended Standards
- 4-Deschlorosertraline (CAS CATO-C4X-134413)
- Blonanserin Impurity 20 (CAS CATO-C4X-111020)
- Verapamil EP Impurity D (CAS 36770-74-8)
- rac-trans-3-Dechloro Sertraline HCl (CAS 91742-83-5)
- L-Ornithine L-Aspartate Impurity 14 TFA Salt (CAS CATO-C4X-253614)
- Doxorubicin Dimer Impurity 23 (CAS 201278-93-5)
- Paracetamol EP Impurity A (CAS 614-80-2)
- 5,5'-Di(9H-fluoren-2-yl)-2,2'-bithiophene (CAS 369599-41-7)
- 1253791-89-7 3195AD C17H15N3O4 Ethyl 5-hydroxy-8-methyl-7-oxo-2-phenyl-7,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylate (CAS 1253791-89-7)
- 2-(5-Methyl-1-phenyl-1H-1,2,3-triazol-4-yl)-4-phenylthiazole (CAS 1207030-53-2)
- Thromboxane B2-d4 (CAS 1346112-79-5)
- Benzyl 2-(((2-aminoethyl)(methyl)amino)methyl)pyrrolidine-1-carboxylate (CAS 1353962-42-1)
- 3-[(4-Pyridinylmethyl)amino]-1-propanol hydrochloride (CAS 1216431-19-4)
- Cycloaspeptide A (CAS 109171-13-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com