Verapamil EP Impurity D (HCl salt) CAS 36770-75-9
| CAS No. | 36770-75-9 |
| Molecular Formula | C14H22ClNO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Verapamil EP Impurity D (HCl salt) (C14H22ClNO2:HCl) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Verapamil EP Impurity D (HCl salt) (CAS 36770-75-9) is a certified pharmaceutical impurity reference standard with the molecular formula C14H22ClNO2:HCl and a molecular weight of 308.24 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Verapamil EP Impurity D (HCl salt) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H22ClNO2 : HCl |
| Molecular Weight | 308.24 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Verapamil Standards
- Verapamil Impurity N1 (CAS 102201-30-9)
- Verapamil Impurity 38 (CAS 114847-42-6)
- Verapamil D6 HCl (CAS 1185032-80-7)
- Verapamil-d7 Hydrochloride (CAS 1188265-55-5)
- Verapamil EP Impurity G (CAS 120-14-9)
- Verapamil EP Impurity J-D7 HCl (CAS 1216413-74-9)
- Verapamil EP Impurity B HCl (CAS 13078-76-7)
- (S)-(-)-Verapamil-d6 Hydrochloride (CAS 1329611-24-6)
Recommended Standards
- Azilsartan Impurity 82 (CAS CATO-C4X-109682)
- Azilsartan Impurity 93 (CAS 1800532-35-7)
- Dimemorfan Phosphate Impurity 5 (CAS CATO-C4X-33585)
- Dabrafenib Impurity 7 (CAS CATO-C4X-30337)
- (3-Butoxy-4-methoxyphenyl)methanol (CAS 161179-23-3)
- 3-(3-Bromophenyl)-1-(m-tolyl)propan-1-one (CAS 898781-97-0)
- 1,2-Dimethyl-5-(trifluoromethyl)-1H-benzo[d]imidazole (CAS 63815-72-5)
- 2-chloro-N-{5-[(diethylamino)sulfonyl]-2-isopropoxyphenyl}acetamide (CAS 1031130-88-7)
- 7,7-Difluoro-5-oxa-2-azaspiro[3.4]octane (CAS 1214875-26-9)
- [14-31]-Semaglutide (CAS CATO-C4X-2226262)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com