Haloperidol Impurity N10 CAS 403-43-0
| CAS No. | 403-43-0 |
| Molecular Formula | C7H4ClFO |
| Molecular Weight | 158.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Haloperidol Impurity N10 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Haloperidol Impurity N10 (CAS 403-43-0, C7H4ClFO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Haloperidol Impurity N10 (C7H4ClFO) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C7H4ClFO |
| Molecular Weight | 158.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
Related Haloperidol Standards
- Haloperidol Impurity 19 (CAS 772-31-6)
- Haloperidol Impurity 16 (CAS 40807-61-2)
- Haloperidol Impurity 37 (CAS 84819-46-5)
- Haloperidol Impurity 23 (CAS 73206-04-9)
- Haloperidol Impurity N1 (CAS 939-52-6)
- Haloperidol Impurity 18 (CAS 2823-19-0)
- Haloperidol Impurity 21 (CAS 3874-54-2)
- Haloperidol impurity 24 (CAS 3110-52-9)
Recommended Standards
- Voriconazole Impurity 48 (CAS 1403893-61-7)
- 2-Chloro-4-(hydroxymethyl)phenol (CAS 105960-29-0)
- 3-Chloro-5-fluorobenzaldehyde 3-chloro-5-fluorobenzaldehyde 97% 3-chloro-5-fluorobenzaldehyde97% 90390-49-1 salor-int l300993-1ea (CAS 90390-49-1)
- 2-Chloro-1-(furan-2-yl)propan-1-one (CAS 106430-52-8)
- Melatonin Impurity 29 (CAS 1020701-51-2)
- Docetaxel Impurity 38 (CAS 196404-55-4)
- Paliperidone Impurity 40 (CAS CATO-C4X-1724140)
- 1,1-Difluoro-4-phenylbutan-2-amine hydrochloride (CAS 1432681-44-1)
- Methyl 5-(pyridin-2-yl)-1,3,4-thiadiazole-2-carboxylate (CAS 1042152-53-3)
- Dimethyl[(4-methylpiperidin-4-yl)methyl]amine (CAS 1343094-97-2)
- tert-butyl 3-formyl-1,10-diazatricyclo[6.4.1.0⁴¹³]trideca-2,4(13),5,7-tetraene-10-carboxylate (CAS 1122597-86-7)
- N'-(4-methylbenzoyl)-1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazole-4-carbohydrazide (CAS 477709-84-5)
- Mesoridazine Besylate (25 mg) (CAS 32672-69-8)
- Semaglutide impurity 198 (CAS CATO-C4X-2226198)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com