Avatrombopag Impurity 32 CAS 41667-95-2
| CAS No. | 41667-95-2 |
| Molecular Formula | C6H3Cl2NO2 |
| Molecular Weight | 192.00 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Avatrombopag Impurity 32 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Avatrombopag Impurity 32 (CAS 41667-95-2) is a certified pharmaceutical impurity reference standard with the molecular formula C6H3Cl2NO2 and a molecular weight of 192.00 g/mol.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Avatrombopag Impurity 32 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 192.00 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C6H3Cl2NO2 |
| Molecular Weight | 192.00 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Avatrombopag Standards
- Avatrombopag Impurity 30 (CAS 73027-79-9)
- Avatrombopag Impurity 43 (CAS 38496-18-3)
- Avatrombopag Impurity 68 (CAS 2325305-38-0)
- Avatrombopag Impurity 85 (CAS 677762-31-1)
- Avatrombopag Impurity 91 (CAS CATO-C4X-223491)
- Avatrombopag Impurity 92 (CAS 160114-74-9)
- Avatrombopag Impurity 143 (CAS 2115508-48-8)
- Avatrombopag Impurity 54 (CAS 28989-50-6)
Recommended Standards
- Favipiravir Impurity 16 (CAS 1023813-21-9)
- 2,6-Dichloro-4-nitrosophenol (CAS CATO-C4X-30364)
- Domperidone Impurity 25 (CAS 3209-22-1)
- 2,4-Dichloronitrobenzene (CAS 611-06-3)
- Ursodeoxycholic Acid Impurity 118 (CAS 83896-19-9)
- Estriol impurity 24 (CAS 104202-84-8)
- Citalopram EP Impurity A (CAS 64372-56-1)
- 4-Hydroxy-6-methyl-2-oxo-2H-pyran-3-carbaldehyde O-(2,4-dichlorobenzyl)oxime (CAS 477868-26-1)
- tert-Butyl ((5-bromo-2-methoxypyridin-3-yl)methyl)carbamate (CAS 334016-81-8)
- 4-Methoxy-5,6,7,8-tetrahydronaphthalene-1-carboxylic acid (CAS 854590-36-6)
- 3-((3-Morpholinopropyl)amino)propanenitrile (CAS 102440-39-1)
- Ethyl 2-(2-acetyl-4-bromophenoxy)acetate (CAS 34849-50-8)
- 2',3',5',6'-Tetrahydrospiro[indoline-3,4'-pyran]-5-carboxylic acid (CAS 1160247-96-0)
- Semaglutide Impurity 21(HO-Ste-L-γGlu-AEEA-AEEA-OH) (CAS 1335440-44-2)
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