Hydroxychloroquine Impurity N75 CAS 4298-11-7
| CAS No. | 4298-11-7 |
| Molecular Formula | C16H22ClN3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Hydroxychloroquine Impurity N75 (CAS 4298-11-7) is a certified pharmaceutical impurity reference standard with the molecular formula C16H22ClN3HCl and a molecular weight of 328.28 g/mol.
Based on its molecular formula C16H22ClN3HCl, Hydroxychloroquine Impurity N75 contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 328.28 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Hydroxychloroquine Impurity N75 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H22ClN3 HCl |
| Molecular Weight | 328.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Hydroxychloroquine Standards
- Hydroxychloroquine Impurity 75 (CAS 100713-49-3)
- Hydroxychloroquine EP Impurity B (CAS 103152-84-7)
- Hydroxychloroquine EP Impurity B Hydrogen sulfate (CAS 103152-84-7(free base))
- Hydroxychloroquine EP Impurity E (CAS 10500-64-8)
- Hydroxychloroquine Impurity 32 (CAS 106007-99-2)
- Hydroxychloroquine Impurity 30 (CAS 1077-74-3)
- Hydroxychloroquine Impurity 53 (CAS 109-83-1)
- Hydroxychloroquine D5 (CAS 118-42-3(Unlabelled))
Recommended Standards
- Rapamycin Impurity 32 (CAS CATO-C4X-174632)
- Olaparib Impurity 95 (CAS CATO-C4X-113595)
- Oxymetazoline Impurity 13 (CAS CATO-C4X-172313)
- 4-Iodo-3-methyl-1H-pyrazol-5-amine (CAS 2055855-82-6)
- (5-Amino-1-(p-tolyl)-1H-pyrazol-4-yl)(o-tolyl)methanone (CAS 618091-15-9)
- 2-Allyloxy-4-nitrophenol (CAS 130636-79-2)
- (2R,3R)-rel-2-methyl-3-Piperidinecarboxylic acid methyl ester (CAS 2455600-70-9)
- 3-(4-Isopropylphenyl)-3-methylbutanoic acid (CAS 416879-41-9)
- (S)-2-amino-3-methyl-1-(4-methylpiperazin-1-yl)butan-1-one (CAS 1217695-67-4)
- Semaglutide impurity 25 (CAS CATO-C4X-222625)
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