Fluticasone Impurity 54 CAS 4571-51-1
| CAS No. | 4571-51-1 |
| Molecular Formula | C24H29FO6 |
| Molecular Weight | 432.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Fluticasone Impurity 54 (CAS 4571-51-1, C24H29FO6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Fluticasone Impurity 54 (C24H29FO6) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Fluticasone Impurity 54 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H29FO6 |
| Molecular Weight | 432.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | F-containing |
Related Fluticasone Standards
- Fluticasone Impurity 96 (CAS CATO-C4X-165096)
- Fluticasone Impurity 83 (CAS CATO-C4X-165083)
- Fluticasone Impurity 84 (CAS CATO-C4X-165084)
- Fluticasone Impurity 111 (CAS 785806-92-0)
- Fluticasone Impurity 112 (CAS CATO-C4X-1650112)
- Fluticasone Impurity 106 (CAS CATO-C4X-1650106)
- Fluticasone Impurity 79 (CAS CATO-C4X-165079)
- Fluticasone Impurity 101 (CAS CATO-C4X-1650101)
Recommended Standards
- 11-Keto Flunisolide (CAS 1997-76-8)
- Osimertinib Impurity 83 (CAS CATO-C4X-204583)
- Triamcinolone Acetonide EP Impurity B (CAS 1260149-96-9)
- Fluocinolone Acetonide EP Impurity E (CAS 68352-03-4)
- Exemestane EP Impurity I (CAS CATO-C4X-164122)
- Amorolfine Impurity 35 (CAS CATO-C4X-154235)
- Atogepant Impurity 66 (CAS CATO-C4X-328566)
- 1231185-85-5 (3R,6aS,11aS)-3,4a,7a-Trihydroxy-10a-methyl-9-(5-oxo-2,5-dihydrofuran-3-yl)hexadecahydro-11bH-cyclopenta[b]phenanthrene-11b-carbaldehyde MFCD15732058 (CAS 1231185-85-5)
- 5-Methyl-5,8-diazaspiro[3.5]nonan-6-one (CAS 2102298-16-6)
- (R)-2-(3-fluoro-4-methylphenyl)-2-(methylamino)ethan-1-ol (CAS 1335506-57-4)
- tert-Butyl (S)-3-(2,4,6-trimethylbenzyl)piperazine-1-carboxylate (CAS 1260605-93-3)
- 2-(2-Methylallyl)benzonitrile (CAS 97780-98-8)
- 5,6-Dihydroxybenzofuran-3-one (CAS 14771-00-7)
- Liraglutide(14-22)TFA Salt (CAS CATO-C4X-199212)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com