Fluticasone Impurity 112 CAS CATO-C4X-1650112
| CAS No. | CATO-C4X-1650112 |
| Molecular Formula | C21H26ClFO4S |
| Molecular Weight | 428.95 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Fluticasone Impurity 112.
CATO supplies Fluticasone Impurity 112 (CAS CATO-C4X-1650112), a pharmacopoeial impurity reference standard (molecular formula C21H26ClFO4S, MW 428.95 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Fluticasone Impurity 112 (C21H26ClFO4S) contains a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 428.95 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Fluticasone Impurity 112 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H26ClFO4S |
| Molecular Weight | 428.95 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related Fluticasone Standards
- Fluticasone Impurity 111 (CAS 785806-92-0)
- Fluticasone Impurity 106 (CAS CATO-C4X-1650106)
- Fluticasone Impurity 101 (CAS CATO-C4X-1650101)
- Fluticasone Impurity 49 (CAS CATO-C4X-165049)
- Fluticasone Impurity 68 (CAS 1744-64-5)
- Fluticasone Furoate Impurity 2 (CAS 1355648-15-5)
- Fluticasone Impurity 54 (CAS 4571-51-1)
- Fluticasone Impurity 96 (CAS CATO-C4X-165096)
Recommended Standards
- 2-((5-(4-Chlorophenyl)-1H-imidazol-2-yl)thio)-N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)acetamide (CAS 337354-66-2)
- 4-(4-tert-Butylphenyl)-2-[4-(3-chlorophenyl)piperazin-1-yl]-4-oxobutanoic acid (CAS 301194-14-9)
- 3-Chloro-2-methyl-N-(4-(2-(4-methylpiperazin-1-yl)-2-oxoethyl)thiazol-2-yl)benzenesulfonamide (CAS 376640-41-4)
- 2-Chloro-5,9,9-triphenyl-9H-fluorene (CAS 2356109-78-7)
- Baricitinib Impurity 75 (CAS CATO-C4X-226075)
- Empagliflozin Impurity 150 (CAS CATO-C4X-1065150)
- Mivacurium chloride Impurity 41 (CAS CATO-C4X-137541)
- 6-(2,5-Dimethylthiophen-3-yl)-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid (CAS 900137-00-0)
- 2-(3,4-dimethoxyphenyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridine (CAS 919747-15-2)
- 3-(3,3-Dimethylbutyl)piperidin-3-ol (CAS 1496402-12-0)
- Ethyl 2-methyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylate (CAS 68301-89-3)
- tert-butyl N-{[3-amino-5-(trifluoromethyl)phenyl]methyl}carbamate (CAS 693249-72-8)
- 3-(1-(2,6-Dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one (CAS 860784-63-0)
- Semaglutide Impurity 21(HO-Ste-L-γGlu-AEEA-AEEA-OH) (CAS 1335440-44-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com