Fluticasone Impurity 106 CAS CATO-C4X-1650106
| CAS No. | CATO-C4X-1650106 |
| Molecular Formula | C22H27F3O5 |
| Molecular Weight | 428.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Fluticasone Impurity 106 is closely related to a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Fluticasone Impurity 106 (CAS CATO-C4X-1650106) is a certified pharmaceutical impurity reference standard with the molecular formula C22H27F3O5 and a molecular weight of 428.44 g/mol.
The molecular framework of Fluticasone Impurity 106 (C22H27F3O5) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H27F3O5 |
| Molecular Weight | 428.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Fluticasone Standards
- Fluticasone Impurity 111 (CAS 785806-92-0)
- Fluticasone Impurity 112 (CAS CATO-C4X-1650112)
- Fluticasone Impurity 101 (CAS CATO-C4X-1650101)
- Fluticasone Impurity 49 (CAS CATO-C4X-165049)
- Fluticasone Impurity 68 (CAS 1744-64-5)
- Fluticasone Furoate Impurity 2 (CAS 1355648-15-5)
- Fluticasone Impurity 54 (CAS 4571-51-1)
- Fluticasone Impurity 96 (CAS CATO-C4X-165096)
Recommended Standards
- Colchicine Impurity 13 (CAS CATO-C4X-141113)
- Procaterol Impurity 46 (CAS CATO-C4X-181046)
- AZD-9574 (CAS 2756333-39-6)
- Nintedanib Impurity 107 (CAS CATO-C4X-1814107)
- Aripiprazole EP Impurity B HCL (CAS 119532-26-2)
- Nafamostat impurity 80 (CAS 2055540-27-5)
- Baricitinib Impurity 116 (CAS CATO-C4X-2260116)
- Cyclohexyl(1-(phenylthio)cyclopropyl)methanol (CAS 127560-56-9)
- 1-(4-Fluorophenyl)pyrrolidin-2-one (CAS 54660-08-1)
- 3-{4-[(2,4-dichlorophenyl)methoxy]phenyl}-1-(4-fluorobenzoyl)-1H-pyrazole (CAS 477711-57-2)
- Loratadine Impurity 15 (CAS 133330-60-6)
- 3-Bromo-4-(2-morpholinoethoxy)benzaldehyde (CAS 258831-64-0)
- 3-(4-Trifluoromethoxyphenyl)Isonicotinic acid (CAS 1261783-07-6)
- Semaglutide impurity 60 (CAS CATO-C4X-222660)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com