Betamethasone Impurity 43 CAS 4735-65-3
| CAS No. | 4735-65-3 |
| Molecular Formula | C24H31BrO6 |
| Molecular Weight | 495.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Betamethasone Impurity 43 (CAS 4735-65-3, C24H31BrO6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Betamethasone Impurity 43 (C24H31BrO6) contains a flavonoid core, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Betamethasone Impurity 43 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H31BrO6 |
| Molecular Weight | 495.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Br-containing |
Related Betamethasone Standards
- Betamethasone impurity 52 (CAS 97168-90-6)
- Betamethasone impurity 67 (CAS 13796-49-1)
- Betamethasone Impurity 144 (CAS CATO-C4X-1437144)
- Betamethasone benzoate (CAS 22298-29-9)
- Betamethasone Impurity 80 (CAS 25092-10-8)
- Betamethasone Valerate EP Impurity H (CAS 52619-18-8)
- Betamethasone Succinate (CAS 27297-42-3)
- Betamethasone Dipropionate EP Impurity D (CAS 5514-81-8)
Recommended Standards
- Bromodesonide (CAS CATO-C4X-13013)
- Aprepitant Impurity 70 (CAS 419574-15-5)
- N-(2,4-Difluorophenyl)-1-methyl-3-(trifluoromethyl)-5-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)-1H-pyrazole-4-carboxamide (CAS 321553-24-6)
- Desonide Bromo Impurity N9 (CAS 39672-77-0)
- Vonoprazan Fumarate Impurity 15 (CAS 636-73-7)
- Levocarnitine Impurity 21 (CAS CATO-C4X-129221)
- Cefixime Impurity 18 (CAS CATO-C4X-113918)
- Mabuterol Impurity 4 (CAS CATO-C4X-14544)
- 5-(3,4-Dimethoxyphenyl)-4h-1,2,4-triazol-3-amine (CAS 289710-95-8)
- 2-Fluoro-5-(3-fluoropiperidin-4-yl)aniline dihydrochloride (CAS 2306262-19-9)
- N-Benzyl-5-bromopyrimidin-2-amine (CAS 38373-55-6)
- 1-(1-Benzyl-2-phenyl-1H-indol-3-yl)ethanone (CAS 62367-66-2)
- 5-Chloro-3-[(3-methoxyphenyl)methyl]-1,2,4-thiadiazole (CAS 946418-99-1)
- Protein Kinase C (alpha) Peptide (CAS 159939-84-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com