Tofacitinib Impurity 42 CAS CATO-C4X-107942

Purity >90%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-107942
Molecular FormulaC13H19N5
Molecular Weight245.32 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Tofacitinib Impurity 42 CAS CATO-C4X-107942 chemical structure

Description

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO supplies Tofacitinib Impurity 42 (CAS CATO-C4X-107942), a pharmacopoeial impurity reference standard (molecular formula C13H19N5, MW 245.32 g/mol) used for the identification and quantification of trace impurities in APIs.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, Tofacitinib Impurity 42 is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 245.32 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

As a certified reference material (CRM), Tofacitinib Impurity 42 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC13H19N5
Molecular Weight245.32 g/mol
Purity>90%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms5

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