Tofacitinib Impurity 227 CAS CATO-C4X-1079227

Description

Compared with other compounds in its class, the molecular weight of 245.32 g/mol gives Tofacitinib Impurity 227 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Tofacitinib Impurity 227 (CAS CATO-C4X-1079227), a pharmacopoeial impurity reference standard (molecular formula C13H19N5, MW 245.32 g/mol) used for the identification and quantification of trace impurities in APIs.

Based on its molecular formula C13H19N5, Tofacitinib Impurity 227 contains a nitrogen-containing heterocyclic scaffold, a nitrile group; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 245.32 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Tofacitinib Impurity 227 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Why CATO?

• ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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