Furosemide EP Impurity E CAS 50-84-0
| CAS No. | 50-84-0 |
| Molecular Formula | C7H4Cl2O2 |
| Molecular Weight | 191.01 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Furosemide EP Impurity E is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 191.01 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Furosemide EP Impurity E (CAS 50-84-0, C7H4Cl2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Furosemide EP Impurity E under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H4Cl2O2 |
| Molecular Weight | 191.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
Related Furosemide Standards
- Furosemide Impurity 57 (CAS 5428-37-5)
- Furosemide Impurity 32 (CAS 18240-50-1)
- Furosemide Impurity 33 (CAS 1803102-41-1)
- Furosemide Impurity 49 (CAS CATO-C4X-140249)
- Furosemide Impurity 57 (CAS 19377-82-3)
- Furosemide Impurity 41 (CAS 137-65-5)
- Furosemide Impurity 34 (CAS 6660-65-7)
- Furosemide Impurity 21 (CAS 30170-04-8)
Recommended Standards
- Aripiprazole Impurity 87 (CAS CATO-C4X-100887)
- Lamotrigine EP Impurity E (CAS 50-45-3)
- 3-Chloro-4-hydroxybenzoyl chloride (CAS 59595-94-7)
- Belumosudil Impurity 67 (CAS CATO-C4X-298867)
- Suvorexant Impurity 48 (CAS CATO-C4X-181248)
- Empagliflozin Impurity 73 (CAS CATO-C4X-106573)
- Tetracaine Impurity 30 (CAS CATO-C4X-192330)
- 6-(4-Methoxyphenyl)-3-methyl-1-phenyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 380187-39-3)
- Methyl 3-(3-chlorophenyl)bicyclo[1.1.1]Pentane-1-carboxylate (CAS 131515-50-9)
- (3S,4R)-1-benzyl-4-methylpiperidin-3-ol (CAS 1932520-43-8)
- 2-(3-Chloro-4-methylphenyl)ethane-1-thiol (CAS 1314902-68-5)
- Febuxostat Impurity 47 (CAS 1346238-10-5)
- 5-(Methylsulfonyl)-1H-indole-2-carboxylic acid (CAS 367501-41-5)
- Insulin Degludec Impurity 26 (CAS CATO-C4X-215726)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com