Furosemide Impurity 57 CAS 5428-37-5
| CAS No. | 5428-37-5 |
| Molecular Formula | C10H8N2O2 |
| Molecular Weight | 188.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Furosemide Impurity 57 (CAS 5428-37-5), molecular formula C10H8N2O2 and molecular weight 188.18 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C10H8N2O2, Furosemide Impurity 57 contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 188.18 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8N2O2 |
| Molecular Weight | 188.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
Related Furosemide Standards
- Furosemide EP Impurity E (CAS 50-84-0)
- Furosemide Impurity 32 (CAS 18240-50-1)
- Furosemide Impurity 33 (CAS 1803102-41-1)
- Furosemide Impurity 49 (CAS CATO-C4X-140249)
- Furosemide Impurity 57 (CAS 19377-82-3)
- Furosemide Impurity 41 (CAS 137-65-5)
- Furosemide Impurity 34 (CAS 6660-65-7)
- Furosemide Impurity 21 (CAS 30170-04-8)
Recommended Standards
- Furan-2-yl benzoate (CAS 20055-18-9)
- Indole-3-glyoxylamide (CAS 5548-10-7)
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- Menatetrenone Impurity 01 (CAS 55700-10-2)
- 4-Bromo-3-(difluoromethyl)-5-methylpyridin-2-ol (CAS 1804855-95-5)
- (4R,5R)-2,2-Dimethyl-1,3-dioxolane-4,5-dimethanamine (CAS 111320-77-5)
- 4-(1-(Dimethylamino)ethyl)phenol hydrochloride (CAS 1049692-05-8)
- 6-Bromo-3-t-butyldimethylsilyloxy-2-fluorophenylboronic acid (CAS 2377608-15-4)
- 5-Amino-1,3,4-oxadiazole-2-carboxamide (CAS 4970-55-2)
- 3-bromo-5-(propan-2-yloxy)phenol (CAS 1026796-73-5)
- N-(sec-Butyl)-6-chloro-2-pyrazinamine (CAS 1220027-83-7)
- [[2-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-oxoethyl]-(phenyl)amino]acetic acid (CAS 1142211-87-7)
- 5-Bromo-7-fluoroquinoline-8-carbaldehyde oxime (CAS 2181779-99-5)
- Liraglutide-d8 Tetratrifluoroacetate (CAS 204656-20-2 (non-labelled, free base))
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